Purification of Pharmaceutical API's, Intermediates, and Fermentation Broths

Removal of reaction by-products, including color bodies and metals, is a critical step in producing high quality pharmaceuticals and intermediates. Ecosorb® multi-functional adsorbents are a family of highly efficient adsorbents combining the rapid kinetics of fine particles with excellent filtration characteristics.

Ecosorb powders can be used in a stirred reactor, or as a precoat or deep bed operating mode, where the adsorbent is added directly to the filter, eliminating contamination of the reaction vessel. Formulations include moist versions, suitable for aqueous systems, as well as low-moisture versions suitable for organic solvents. Since each reaction/solvent system is unique, Graver provides a “sample kit” containing a broad range of adsorbent types for screening specific applications.

Application Notes

  • GTX 304: Ecosorb Products for Pharmaceutical Purification

Data Sheets

  • C-906 Data Sheet - color, reaction by-products (Coming soon – contact your Graver representative for our most recent information)
  • C-910 Data Sheet - PM catalysts, color reaction by-products (Coming soon – contact your Graver representative for our most recent information
  • C-941 Data Sheet - PM catalysts
  • C-944 Data Sheet - PM catalysts (Coming soon – contact your Graver representative for our most recent information)
  • C-950 Data Sheet - Color, Polar contaminants (Coming soon – contact your Graver representative for our most recent information)
  • C-952 Data Sheet - Color, Polar contaminants (Coming soon – contact your Graver representative for our most recent information)
  • C-971 Data Sheet - Divalent heavy metals cations
  • C-981 Data Sheet - Color, contaminants from fermentation broth, Anionic contaminants

Ecosorb PAK® adsorbent cartridges are sold as a complete unit in Graver-supplied housings, or can be used in many commonly used filter housings with retrofit kits from Graver. Ecosorb PAK adsorbent cartridges eliminate reactor vessel and filter cleanup, and simplify the recovery of precious metals.

E-Pak® Process Scale Adsorbent Cartridges – Product Overview

Graver E-Pak® Radial Flow Adsorbent Cartridge  E-Pak® Adsorbent Cartridges  Laboratory Scale E-Pak® Housing