发酵

在发酵过程中,发酵过程需要极高的清洁度和微生物控制水平,随后会产生高密度的真菌、酵母或细菌生物质以及其他溶解的固体,必须从液相(通常含有目标化合物)中分离出来。因此,该工艺的所有原料,例如原料、水和空气,都必须经过处理,以防颗粒和潜在的微生物污染。发酵过程结束后,必须对微生物风险进行持续管理,还需要采用有效的方法来处理高固体溶液,以产生高浓度的生物质和较高的浓缩目标分子的回收率。

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